基本简介

职称:教授

学位:博士

毕业学校:武汉理工大学

主要兼职:广东省功能生物材料工程技术研究中心主任

电子邮件:cesqdp@mail.sysu.edu.cn

个人主页:无

学历

本科:复旦大学

硕士:武汉理工大学

博士:武汉理工大学

学术经历

博士后:太阳集团tyc138化学与化学工程学院
 

学科方向

所在学科:高分子化学与物理

研究方向:生物医用高分子材料与组织工程

研究兴趣:组织损伤修复与再生医学基础研究、临床应用与产品开发。生物医用高分子材料包括各种功能性的可吸收聚酯、不同组织来源的脱细胞基质与水凝胶、以及具有良好生物相容性的聚羟基丙烯酸酯类等。应用领域如中枢神经(脑、脊髓)、外周神经、骨折内固定、眼科、心血管、皮肤、椎间盘等。

学术业绩

      从事生物医用高分子材料及组织工程研究,承担过7项国家基金项目,作为课题负责人和研究骨干参加2项国家十三五重点研发项目,在可吸收聚酯的合成与加工、生物源性脱细胞基质材料以及组织损伤修复再生的应用研究方面发表论文130多篇,获得发明专利20多件,出版专著1部。

荣誉获奖

作为主要参与者的组织工程神经系列研究获得广东省科技进步一等奖。

代表论著

1. Rongli Deng, Ziling Luo, Zilong Rao, Zudong Lin, Shihao Chen, Jing Zhou, Qingtang Zhu, Xiaolin Liu, Ying Bai* & Daping Quan*. Decellularized Extracellular Matrix Containing Electrospun Fibers for Nerve Regeneration: A Comparison Between Core–Shell Structured and Preblended Composites. Advanced Fiber materials, 2022

2. Sheng Liu, Zilong Rao, Jianlong Zou, Shihao Chen Qingtang Zhu, Xiaolin Liu, Ying Bai,* Yizhi Liu,* Daping Quan*. Properties regulation and biological applications of decellularized peripheral nerve matrix hydrogel. ACS Applied Bio Materials.2021,4,8,6473-6487

3. Rui Li, Jinghui Xu, Zilong Rao, Rongli Deng, Yiwei Xu, Shuai Qiu, Houqing Long, Qingtang Zhu, Xiaolin Liu, Ying Bai*, and Daping Quan*. Facilitate Angiogenesis and Neurogenesis by Growth Factors Integrated Decellularized Matrix Hydrogel. Tissue Engineering Part A 2021,  doi: 10.1089/ten.tea.2020.0227

4. Yiwei Xu, Jing Zhou, Cuicui Liu, Sheng Zhang, Fenglin Gao, Wenjing Guo, Xiumin Sun, Chi Zhang, Heying Li, Zilong Rao, Shuai Qiu, Qingtang Zhu, Xiaolin Liu, Xiaodong Guo, Zengwu Shao, Ying Bai*, Xiao Zhang*, and Daping Quan*. Understanding the Role of Tissue-Specific Decellularized Spinal Cord Matrix Hydrogel for Neural Stem/Progenitor Cell Microenvironment Reconstruction and Spinal Cord Injury. Biomaterials 2021, 268: 120596. doi: 10.1016/j.biomaterials.2021.120596

5. Zilong Rao#, Tao Lin#, Shuai Qiu, Jing Zhou, Sheng Liu, Shihao Chen, Tao Wang, Xiaolin Liu, Qingtang Zhu*, Ying Bai*, Daping Quan*. Decellularized nerve matrix hydrogel scaffolds with longitudinally oriented and size-tunable microchannels for peripheral nerve regeneration. Materials Science & Engineering C 2021, 120: 111791. doi: 10.1016/j.msec.2021.111791

6. Chi Zhang, Peng Dong, Ying Bai⁎, Daping Quan⁎, Nanofibrous polyester-polypeptide block copolymer scaffolds with high porosity and controlled degradation promote cell adhesion, proliferation and differentiation. European Polymer Journal 2020, 130, 109647. doi: 10.1016/j.eurpolymj.2020.109647

7. Shihao Chen, Zhaoyi Du, Jianlong Zou, Shuai Qiu, Zilong Rao, Sheng Liu, Xiumin Sun, Yiwei Xu, Qingtang Zhu, Xiaolin Liu, Hai-Quan Mao, Ying Bai*, Daping Quan*. Promoting Neurite Growth and Schwann Cell Migration by Harnessing Decellularized Nerve Matrix onto Nanofibrous Guidance. ACS Applied Materials & Interfaces 2019, 11: 17167-17176 .

8. Xiumin Sun, Ying Bai, Hong Zhai, Sheng Liu, Chi Zhang, Yiwei Xu, Jianlong Zou, Tao Wang, Shihao Chen, Qingtang Zhu, Xiaolin Liu, Haiquan Mao, Daping Quan*. Devising micro/nano-architectures in multi-channel nerve conduits towards a pro-regenerative matrix for the repair of spinal cord injury. Acta Biomaterialia. 2019, 86: 194-206.

9. Jian-Long Zou, Sheng Liu, Jia-Hui Sun, Wei-Hong Yang, Yi-Wei Xu, Zi-Long Rao, Bin Jiang, Qing-Tang Zhu, Xiao-Lin Liu, Jin-Lang Wu, Calvin Chang, Hai-Quan Mao, Eng-Ang Ling, Da-Ping Quan,* and Yuan-Shan Zeng*. Peripheral Nerve-Derived Matrix Hydrogel Promotes Remyelination and Inhibits Synapse Formation. Adv. Funct. Mater. 2018, 28: 1705739

10.Shuo Tang, Jixiang Zhu, Yangbin Xu, Andy Peng Xiang, Mei Hua Jiang, Daping Quan*, “The effects of gradients of nerve growth factor immobilized PCLA scaffolds on neurite outgrowth in vitro and peripheral nerve regeneration in rats”, Biomaterials. 2013, 34: 7086-7096